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MAPK inhibition

Showing 1 - 25 of 3,014
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Rosacea, Erythematotelangiectatic Trial in Albany (Trametinib)

Recruiting
  • Rosacea, Erythematotelangiectatic
  • Albany, New York
    Samuel S. Stratton VA Medical Center
Nov 9, 2022

Metastatic Thyroid Cancer Trial in Essen (Trametinib 2 MG [Mekinist], Trametinib 2 MG [Mekinist] and Dabrafenib 75 MG (2-0-2)

Recruiting
  • Metastatic Thyroid Cancer
  • Trametinib 2 MG [Mekinist]
  • Trametinib 2 MG [Mekinist] and Dabrafenib 75 MG (2-0-2) [Tafinlar]
  • Essen, Northrhine-Westphalia, Germany
    Manuel M. Weber
May 17, 2022

NSCLC, KRAS Mutation-Related Tumors Trial in Philadelphia (Binimetinib Pill, Hydroxychloroquine Pill)

Recruiting
  • Non-Small Cell Lung Cancer
  • KRAS Mutation-Related Tumors
  • Binimetinib Pill
  • Hydroxychloroquine Pill
  • Philadelphia, Pennsylvania
    Abramson Cancer Center of the University of Pennsylvania
Sep 30, 2022

Metastatic Colorectal Adenocarcinoma, Refractory Colorectal Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8 Trial (drug,

Not yet recruiting
  • Metastatic Colorectal Adenocarcinoma
  • +2 more
  • BET Bromodomain Inhibitor ZEN-3694
  • +6 more
  • (no location specified)
Oct 25, 2023

COVID-19 Trial in Worldwide (Losmapimod oral tablet, Placebo oral tablet)

Terminated
  • COVID-19
  • Losmapimod oral tablet
  • Placebo oral tablet
  • Irvine, California
  • +15 more
Mar 30, 2022

Melanoma (Skin) Trial in Dijon, Thionville, Vandœuvre-lès-Nancy (Blood sampling)

Active, not recruiting
  • Melanoma (Skin)
  • Blood sampling
  • Dijon, France
  • +3 more
Mar 29, 2022

Metastatic Melanoma Trial in Netherlands (drug, device, procedure)

Terminated
  • Metastatic Melanoma
  • Vemurafenib plus cobimetinib
  • +3 more
  • Amsterdam, Netherlands
  • +9 more
Nov 24, 2022

BRAF-/MEK-Inhibition With Dabrafenib and Trametinib in Melanoma

Active, not recruiting
  • Melanoma
  • Dabrafenib and Trametinib
  • Buxtehude, Niedersachsen, Germany
  • +35 more
Aug 25, 2022

Uveal Melanoma Trial in New York, Houston (Selumetinib)

Active, not recruiting
  • Uveal Melanoma
  • New York, New York
  • +2 more
Jun 28, 2022

SARS (Severe Acute Respiratory Syndrome) Trial in Sousse, Sahloul (Quercetin, Placebo)

Completed
  • SARS (Severe Acute Respiratory Syndrome)
  • Sousse, Itinéraire Ceinture Cité Sahloul, Tunisia
  • +1 more
Jan 2, 2023

IBD Trial (Metformin)

Not yet recruiting
  • Inflammatory Bowel Diseases
  • (no location specified)
Nov 10, 2022

Solid Tumor, Adult Trial in Worldwide (ASTX029)

Recruiting
  • Solid Tumor, Adult
  • Duarte, California
  • +26 more
Nov 18, 2022

Advanced Malignant Solid Tumor, Recurrent Ependymal Tumor, Recurrent Ewing Sarcoma Trial in Puerto Rico, United States

Active, not recruiting
  • Advanced Malignant Solid Neoplasm
  • +35 more
  • Birmingham, Alabama
  • +108 more
Oct 19, 2022

Advanced or Metastatic Solid Tumors Trial (Naporafinib, Trametinib)

Not yet recruiting
  • Advanced or Metastatic Solid Tumors
  • (no location specified)
Jun 21, 2023

NSCLC, Ovarian Cancer, Melanoma Trial in Worldwide (LXH254, PDR001)

Terminated
  • NSCLC
  • +3 more
  • Boston, Massachusetts
  • +17 more
Dec 20, 2022

Adamantinous Craniopharyngioma, Recurrent Adamantinomatous Craniopharyngioma Trial in Worldwide (Binimetinib Oral Tablet

Not yet recruiting
  • Adamantinous Craniopharyngioma
  • Recurrent Adamantinomatous Craniopharyngioma
  • Binimetinib Oral Tablet [Mektovi]
  • Aurora, Colorado
  • +17 more
Nov 28, 2022

Metastatic Colorectal Cancer Trial in Tanta (Silymarin)

Not yet recruiting
  • Metastatic Colorectal Cancer
  • Tanta, Egypt
    faculty of Pharmacy , Tanta University
Dec 8, 2022

Advanced Cancer, Metastatic Cancer, Solid Tumor Trial in United States (JZP815)

Recruiting
  • Advanced Cancer
  • +2 more
  • Denver, Colorado
  • +4 more
Jan 10, 2023

Advanced Solid Tumors With MAPK Pathway Mutations Trial in Nedlands (D3S-002)

Not yet recruiting
  • Advanced Solid Tumors With MAPK Pathway Mutations
  • Nedlands, Western Australia, Australia
    D3 Bio Investigative Site
May 24, 2023

Plexiform Neurofibroma, Neurofibromatosis Type 1 (NF1) Trial in United States (Mirdametinib (PD-0325901) oral capsule or

Active, not recruiting
  • Plexiform Neurofibroma
  • Neurofibromatosis Type 1 (NF1)
  • Mirdametinib (PD-0325901) oral capsule or dispersible tablet
  • Birmingham, Alabama
  • +49 more
Nov 17, 2022

Resistance-associated Mutations in Metastatic Lung Cancer

Recruiting
  • Lung Cancer
  • Liquid biopsy
  • Monza, MB, Italy
    Fondazione IRCCS San Gerardo dei Tintori
Oct 10, 2023

Solid Tumor, Advanced Solid Tumor, Non Small Cell Lung Cancer Trial in Denver, Nashville, Fairfax (MRTX0902, MRTX849)

Recruiting
  • Solid Tumor
  • +3 more
  • Denver, Colorado
  • +2 more
Dec 19, 2022

Renal Cell Carcinoma Trial in Omaha, Cleveland, Philadelphia (Axitinib)

Terminated
Has Results
  • Renal Cell Carcinoma
  • Omaha, Nebraska
  • +2 more
Jul 26, 2021

Metastatic or Locally Advanced Malignancies Trial in Germany (Vemurafenib, Cobimetinib, Atezolizumab)

Recruiting
  • Metastatic or Locally Advanced Malignancies
  • Berlin, Germany
  • +5 more
Jan 2, 2023

Leukemia, Myelodysplastic Syndrome(MDS) Trial in Duarte, Houston (fadraciclib)

Recruiting
  • Leukemia
  • Myelodysplastic Syndrome(MDS)
  • Duarte, California
  • +1 more
Apr 1, 2022